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Keywords: Spike detection; Spike sorting; Spike train analysis; Extra-cellular recording; Tetrode; Electrophysiology; Multi-unit recording; Single-unit recording; Cluster analysis; Superposition resolution; MATLAB; Accuracy quantification; Object Oriented Programming;
Data simulation; Neuroshare Native
 
     
 

NeuroMAX Toolbox: Overview                       


Description

NeuroMAX is a MATLAB-based software toolbox for the analysis of spike train data. You’ll use NeuroMAX to create a chain of powerful analysis tools that meet your specific research goals. This tool chain, or Workspace, can be any combination of packaged NeuroMAX tools and your own custom MATLAB-based tools.

NeuroMAX tools are grouped into four toolboxes: Spike Detection, Spike Sorting, Spike Train Analysis, and Display Tools. For a summary of a particular toolbox, select the matching button to the left. From there, you can access individual tools within that toolbox.

Using MATLAB’s proven programming structure, you can easily convert your unique analysis algorithms into an additional tool in one of the NeuroMAX toolboxes

Downloading NeuroMAX Tools

Each NeuroMAX tool is available as part of the NeuroMAX Toolbox and as MATLAB command line code (.m file). We encourage you to download either an evaluation copy of the NeuroMAX toolbox, or m-files of selected analysis tools that are of particular interest to you. These command line tools can be run directly from MATLAB. Download a sample Neuroshare Native (NsN) data file and put our tools to the test, or use the tools to perform individual analyses on your own NsN data. A PDF instruction file is included with each tool.

If you’ve already registered as a “Visitor”, click DOWNLOAD to continue to the download page. Otherwise, click REGISTER and continue with the quick visitor registration page. You’ll then be lead to the Download page. You can also access the Download page directly from any individual tool page.

The NeuroMAX Workspace

File Compatibility:

To provide maximum compatibility with a large variety of commercial data acquisition systems, NeuroMAX toolboxes operate on data files saved to the NsN data file format. The output of each NeuroMAX tool is also an .nsn file, based on NsN specifications. For details about the NsN format, please visit http://neuroshare.sourceforge.net/index.shtml

Parameter Settings:

All NeuroMAX tools come with default parameters so you see immediate feedback of tool operation on a given data set. Of course, you can also create a customized set of parameters to reveal specific information from your unique recording session.

Data Processing Protocol:

The combination of large raw data files (multiple channels and long recording times) and complex analysis sequences can lead to frustratingly long screen update rates, particularly during the parameter setup process. To solve this problem, NeuroMAX incorporates a distinctive feature called the “Analysis Segment”. This segment is small enough to be easily processed in MATLAB, but large enough to be representative of the raw data file.

The selected Analysis Segment is re-analyzed as you change a tool’s parameters, and the results are graphed in the tool’s display screen. This lets you visually verify the settings by reviewing displays of analyzed segments prior to processing the entire data file. You can choose an immediate display update as you modify each parameter, or opt for a delayed graphics update, letting you change multiple settings prior to a screen rewrite.

Once you are satisfied with each tool’s parameter settings, simply apply the tool chain to the complete input data set in an offline, non-interactive mode. The input to each tool is either raw data, or the output from a previous tool. The analyzed result of each tool is saved as an .nsn file. You also have access to intermediate results from each tool application.

Flexible Graphics Displays:

A major component of neuroscience research is the publication of data and papers. All NeuroMAX tool modules allow display axes to be exported to standard MATLAB figure windows that can be annotated and saved in various image formats.

 

 
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Last Updated: 07-Apr-2008