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Keywords: Spike detection; Spike sorting; Spike train analysis; Extra-cellular recording; Tetrode; Electrophysiology; Multi-unit recording; Single-unit recording; Cluster analysis; Superposition resolution; MATLAB; Accuracy quantification; Object Oriented Programming;
Data simulation; Neuroshare Native
 
     
   

Collaborative Research : Application                      



Overview

The NeuroMAX toolboxes (Spike Detection, Spike Sorting, Spike Train Analysis, and Display Tools) address several specific deficiencies of software tools currently available to the electrophysiology community. Most importantly, NeuroMAX enhances the ability of researchers to easily collaborate and share algorithms and processing results by providing a consistent data processing and results visualization software platform.

Several key features of NeuroMAX have been implemented specifically to encourage collaborative research among researchers in the neuroscience community. These include the fact that NeuroMAX is built in MATLAB, with an open implementation platform1, and utilizes the Neuroshare Native (NsN) data format

MATLAB Coded

NeuroMAX is a “plug-in” to the successful and widely available MATLAB environment, specifically with its Object Oriented Programming (OOP) architecture. MATLAB provides an environment that is conducive to quickly producing workable prototypes for testing. Building on MATLAB gives you the power to leverage its flexible display and analysis tools.

In addition, there are numerous third party applications compatible with MATLAB that offer processing time speed-up, including products that will compile MATLAB code to C and C++ for re-hosting on high performance computers. Because NeuroMAX starts with MATLAB, a platform that is commonly found in research labs, its tools and results can be readily shared with the research community.


Open Implementation Platform1

The NeuroMAX toolboxes are offered in an open implementation platform1 format to facilitate user modifications and additions. The MATLAB m-files are always available, either for modification or as a starting point for the creation of new tools unique to your application.

NsN Common Data Format


Data input and storage are based on the Neuroshare Native (NsN) open standards format. From the Neuroshare website (http://neuroshare.sourceforge.net/index.shtml): “The neuroshare.org website is a collaborative, vendor-neutral area dedicated to public domain standards and software for neurophysiology.”

Because the input data to NeuroMAX and the results of NeuroMAX analyses are saved in .nsn format, raw data and results files can be readily shared among researchers.

NsN input/output formats include:

         Analog (continuous data streams)

         Segment (non-continuous blocks of data)

         Event (small time-stamped text or binary data that represent discrete events such as trial markers, embedded user comments, or digital input values).

         Neural Event (timestamps of events that are known to represent neural action potential firing times).

Another primary goal of using these widely available tools and formats is the sharing of user-created analysis algorithms within the neuroscience community. As the last step in this process, we will periodically release user-submitted, R.C. Electronics Inc., evaluated tools for the NeuroMAX toolboxes via the NeuroMAX website, neuromax.org.

1 Open implementation platform: allows developers of a program to alter pieces of the underlying software to fit their specific needs. Because we provide the standard tools and structures, you don’t have to start with a blank slate when creating a unique analysis algorithm.

   
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Last Updated: 27-Mar-2008